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Pregabalin

Price: 15 INR

Pregabalin is an analog of the neurotransmitter GABA. It binds potently to the alpha2-delta subunit resulting in modulation of Ca channels and reduction in the release of several neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P. Absorption: Rapidly absorbed after oral doses. Peak plasma concentrations are achieved within 1.5 hr. Distribution: Not bound to plasma proteins. Metabolism: Negligible metabolism. Excretion: About 98% excreted unchanged in urine. Elimination half life: about 6.3 hr.

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